Table 6. Biological activity from Indonesian marine by-product and its component

By product source Biological activity and value Protein, bioactive peptides, amino acids or nitrogen content of hydrolysate
Milkfish skin (collagen extraction) (Wibawa et al., 2015) NA Protein (0.407 mg/mL)
Dolphin fish Coryphaena hippurus (Thenu et al., 2017) NA Protein (19.16%), proline (3.32%), arginine (3.01%), serine (2.85%), phenylalanine (2.65%). Cystine, histidine, valine and methionine (< 2%)
Mackerel Scomberjaponicus heads (Setijawati et al., 2019) Alternative peptone for bacterial growth medium. Improve biomass of Escherichia coli (from control 61.04% to 76.85%), Staphylococcus aureus (from control 48.24% to 56.08%), Salmonella thypi (from control 59.46% to 71.04%), and Aeromonas hydrophila (from control 49.83% to 54.15%) Nitrogen (11.53%)
Grouper Epinephelus fuscoguttatus head (Jaziri et al., 2020) Alternative peptone for bacterial growth medium. Improve biomass of E. coli (from control 42.81% to 64.63%) and S. aureus (from control 35.74% to 59.38%) Peptone yield (4.61%-5.70%), protein (85.08%-86.43%), glycine (21.48%), glutamic acid (10.67%), alanine (10.26%), proline (8.99%), arginine (8.16%) and aspartic acid (7.60%). Tyrosine, and histidine were less than 3%
Parrotfish Scarus javanicus head (Jaziri et al., 2020) Alternative peptone for bacterial growth medium. Improve biomass of E. coli (from control 25.87% to 50.33%) and S. aureus (from control 33.20% to 55.63%) Peptone yield (3.27%-3.45%), protein (83.80%-86.67%), glycine (21.34%), glutamic acid (10.12%), alanine (8.97%), proline (8.94%), aspartic acid (7.76%), and phenylalanine (6.73%). Tyrosine and histidine were less than 3%
Parrotfish Chlorurussordidus head (Prihanto et al., 2019) Antioxidant (DPPH 58.2%) Protein (69.15%), glutamic acid (14.43%), aspartic acid (11.06%), leucine (8.48%), lysine (8.3%), glycine (7.63%) and alanine (7.41%). Serine and histidine were less than 3%
Milkfish Chanos chanos skin (Kusumaningtyas et al., 2019) Antioxidant (ABTS 80%-90%) and antifungal (Candida albicans ~5 Log CFU/mL) NA
Grouper E. fuscoguttatus swim bladder (collagen hydrolysate) (Trilaksani et al., 2020) Collagen extract suitable for cosmetic material Protein (75.20%), glycine (102.04%), proline (48.20%), alanine (41.11%), glutamic acid (35.68%), aspartic acid (19.98%), serine (18.02%)
Bigeye tuna Thunnus obesus skin (collagen) (Devita et al., 2021) Antioxidant (DPPH 0.18-0.46 mg AAE/g) Protein (6.58%-16.37%)
Yellowfin tuna Thunnus albacares skin (collagen hydrolysate) (Nurilmala et al., 2019) Antioxidant (IC50 251.23 ppm), antiglycation (4.36%) Glycine (175.75 mg/g), proline (70.44 mg/g), arginine (64.10 mg/g), glutamic acid (58.37 mg/g), alanine (54.72 mg/g), aspartic acid (27.66 mg/g)
Mackerel by-product (Setijawati et al., 2020) Alternative peptone for bacterial growth medium Soluble protein (0.98-2.10 g/L), lysine (16.73%), glutamic acid (12.74%), alanine (9.32%), aspartic acid (8.74%), proline (8.73%), arginine (6.91%)
Mackerel S. japonicus head (Nurdiani et al., 2022) Antioxidant (DPPH 15.64%-36.95%) Serine (21.16%), glycine (13.27%), histidine (7.99%), aspartic acid (6.82%), alanine (6.74%), glutamic acid (6.17%)
Blue swimming crab Portunus pelagicus hepatopancreas (Fadilah et al., 2020) NA Protein (49.21%), glutamic acid (3.75%), leucine (2.41%), arginine (2.13%), aspartic acid (1.96%), valine (1.84%), glycine (1.65%)
NA, not available; DPPH, 2,2-diphenyl-1-picrylhydrazyl; ABTS, 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid; AAE, ascorbic acid equivalent; IC50, half maximal inhibitory concentration.