Apostichopus japonicus | Protein hydrolysates | Zebrafish model | Inhibition of inflammation-associated leukocyte recruitment | Zhang et al., 2021 |
Cucumaria frondose | Sterol sulfate | RT-qPCR | Pro-inflammatory cytokine inhibition | Zhang et al., 2020 |
Holothuria arguinensis | Crude extracts | COX-2 inhibitory assay | COX-2 inhibition | Carletti et al., 2022 |
Holothuria leucospilota | Methanol extract | RAT | Hind paw edema | Moradi et al., 2020 |
H. leucospilota | Methanol extract | BLAB/C mice model | COX-2 inhibition | Sasongko et al., 2020 |
Holothuria scabra | Crude ethyl acetate extract | Cell culture | NF-κB and JNK inhibition | Pranweerapaiboon et al., 2020 |
Isostichopus badionotus | Glycosaminoglycan-rich fraction | Male CD1 and C57Bl/6 | Down-regulate TPA-induced inflammatory responses | Olivera-Castillo et al., 2020 |
Stichopus japonicus | Major yolk protein | C57BL/6J male mice | Prevents tissue damage, diminished occult diarrhea and bleeding | Feng et al., 2022 |