Alkaloid | Alkaloid guanidine: Zetekitoxin-AB | | Antibacterial activity of Escherichia coli MIC is 10 μg/mL | (Yotsu-Yamashita et al., 2004) |
Alkaloid indol: bufotenine | No | Anti-tumor activity | (Renda et al., 1985) |
Lipophilic alkaloids: Pyrrolizidine | | The MIC antibacterial activity was 3.9 μg/mL against Staphylococcus aureus and 31.3 μg/mL against E. coli | (Daly et al., 2005) |
Bombesin | Bombesin-likes substances (Bbs-LS) | No | Stimulates the release of the stomach hormone gastrin | (Park et al., 1989) |
Bbs-14 SyntheticRP- Bombesin | GGNQWAIGHFM-NH2 | Antibacterial activity of S. aureus with MIC of 25 μg/mL, stimulating the release of gastric hormone gastrin | (de Sousa et al., 2022) |
Brevinin | Brevinin 1 | FLPVLAGIAAPALFCKITKKC | Antibacterial activity of E. coli with MIC of 26 μg/mL, stimulates insulin release | (Conlon et al., 2008b) |
Brevinin 2 | GLLDSLKGFAATAGKGVLQSLLSTASCKLAKTC |
Brevinin-2GU | GVIIDTLKGAAKTVAAELLRKAHCKLTNSC | Significantly reduces the production of TNF-α from concanavalin A (Con A)-stimulated PBM cellsSuppression of IFN- production from unstimulated PBM cells | (Popovic et al., 2012) |
Magainin | Magainin 1 | GIGKFLHFAGKFLKAFVLEIMKF | Resistance to E. coli D31 with MIC of 5 μg/mL and S. aureus MIC of 50 μg/mL | (Zasloff, 1987a) |
Magainin 2 | GIGKFLHFAKKFLKAFVLEIMNF |
Magainin A | AIGKFLHAAKKFAKAFVAEIMNF | Anticancercontraceptive, antifungal and antiviral activity | (Ohsaki et al., 1992) |
Magainin G | GIGKFLHSAGKFGKAFVGEI |
Other compounds | Cruzioseptin-16 | GFLDVLKGVGKAALGAVTHLINQGEQ | Resistant to bacteria | (Cuesta et al., 2021) |
Cruzioseptin-17 | GFLDVLKGVGKAALGAVTHLINQGEQ |
Esculentin-1a | GIFSKLAGKKIKNLLISGLKG-NH2 | Stimulation of HaCaT cell migration and gram-negative antibacterial activity. Pseudomonas aeruginosa | (Di Grazia et al., 2015) |
Ocellatin-4 | GLLDFVTGVGKDIFAQLIKQI-NH2 | Resistant to bacteria | (Nascimento et al., 2004; Nascimento et al., 2007) |
Phylloseptin-L2 | FLSLIPHVISALSSL | Stimulates insulin release | (Abdel-Wahab et al., 2008) |
Plasticin-L1 | GLVNGLLSSVLGGGQGGGGLLGGI-Xaa | Stimulates insulin release | (Conlon et al., 2009) |
Proline-arginine | ELRLPEIARPVPEVLPARLPLPALPRN | Stimulates insulin release | (Carta et al., 2021) |
Rhinophrynin-27Syphaxin | No | Resistant to bacteria | (Dourado et al., 2007) |