Table 2. Collagenase, elastase, and hyaluronidase inhibitory effects of green seaweed extracts

Green seaweeds	Total phenolic contents (PGE mg/g)	IC₅₀ values for collagenase inhibition (μg/mL)	IC₅₀ values for elastase inhibition (μg/mL)	IC₅₀ values for hyaluronidase inhibition (μg/mL)
Chaetomorpha moniligera	29.59 ± 0.52^b	> 100	> 1,000	> 250
Cladophora albida	9.12 ± 0.15^e	> 100	> 1,000	> 250
Cladophora wrightiana var. minor	39.95 ± 0.50^a	77.14 ± 0.31	> 1,000	93.24 ± 2.18
Codium fragile	3.12 ± 0.10^j	> 100	> 1,000	> 250
Codium subtubulosum Okamura	1.29 ± 0.00^l	> 100	> 1,000	> 250
Codium tenuifolium	2.50 ± 0.14^k	> 100	> 1,000	> 250
Ulothrix flacca	22.60 ± 0.69^c	> 100	> 1,000	> 250
Ulva australis	15.95 ± 0.42^d	> 100	> 1,000	> 250
Ulva compressa	6.43 ± 0.18^h	> 100	> 1,000	> 250
Ulva intestinalis	4.07 ± 0.02ⁱ	> 100	> 1,000	> 250
Ulva linza	7.47 ± 0.17^g	> 100	> 1,000	> 250
Ulva ohnoi	8.57 ± 0.18^f	> 100	> 1,000	> 250
Ulva prolifera	9.34 ± 0.25^e	> 100	> 1,000	> 250
Umbraulva japonica	3.39 ± 0.07^j	> 100	> 1,000	> 250
EGCG¹⁾ (mM)		0.17 ± 0.01	2.34 ± 0.07	0.25 ± 0.00

Positive control.
Small letters presented differences between treatments in each column.
EGCG, epigallocatechin gallate; IC₅₀, half-maximal inhibitory concentration; PGE, phloroglucinol equivalent.