Table 9. Comparison of collagen optimized conditions through response surface methodology (RSM) with machine learning approaches
SI no.
Exposure to ultrasound (min)
Temperature of the solvent (°C)
Collagen – (
R
2
value)
Experimental
RSM
ANN
kNN
Random forest
1
30.45
38.8
1.7263
1.812 (0.93)
1.727 (0.969)
1.734 (0.682)
1.642 (0.923)
ANN, artificial neural network; kNN, k-nearest neighbors.