Table 3. Dipeptidyl peptidase-IV (DPP-IV) inhibitory activity of 181 plant extracts
| Sample no. | Inhibitory activity (%) | Sample no. | Inhibitory activity (%) |
| Ile-Pro-Ile | 86 ± 0.31**** | 43. | 51 ± 0.53**** |
| 1. | 51 ± 2.55**** | 44. | 52 ± 0.61**** |
| 2. | 54 ± 2.23**** | 45. | 50 ± 1.46**** |
| 3. | 54 ± 0.921), **** | 46. | 51 ± 0.96**** |
| 4. | 55 ± 5.971), **** | 47. | 49 ± 1.07**** |
| 5. | 50 ± 2.40**** | 48. | 49 ± 1.07**** |
| 6. | 48 ± 0.80**** | 49. | 52 ± 1.86**** |
| 7. | 51 ± 0.41**** | 50. | 52 ± 1.00**** |
| 8. | 52 ± 0.85**** | 51. | 50 ± 1.61**** |
| 9. | 52 ± 2.11**** | 52. | 53 ± 1.84**** |
| 10. | 49 ± 1.16**** | 53. | 47 ± 1.96**** |
| 11. | 53 ± 4.39**** | 54. | 16 ± 1.86**** |
| 12. | 53 ± 3.08**** | 55. | 51 ± 0.46**** |
| 13. | 50 ± 0.81**** | 56. | 53 ± 1.51**** |
| 14. | 50 ± 0.70**** | 57. | 53 ± 1.92**** |
| 15. | 52 ± 2.00**** | 58. | 50 ± 0.70**** |
| 16. | 50 ± 1.01**** | 59. | 53 ± 1.33**** |
| 17. | 47 ± 0.55**** | 60. | 51 ± 0.96**** |
| 18. | 49 ± 0.85**** | 61. | 51 ± 1.61**** |
| 19. | 52 ± 5.48**** | 62. | 12 ± 1.08** |
| 20. | 52 ± 2.65**** | 63. | 12 ± 1.08** |
| 21. | 48 ± 0.85**** | 64. | 16 ± 1.42**** |
| 22. | 55 ± 1.591), **** | 65. | 13 ± 1.42*** |
| 23. | 49 ± 0.55**** | 66. | 7 ± 0.82 |
| 24. | 52 ± 2.39**** | 67. | 8 ± 1.42 |
| 25. | 48 ± 0.55**** | 68. | 13 ± 1.48*** |
| 26. | 50 ± 0.81**** | 69. | 11 ± 2.49** |
| 27. | 53 ± 3.99**** | 70. | 11 ± 2.69** |
| 28. | 52 ± 0.93**** | 71. | 10 ± 2.56** |
| 29. | 50 ± 3.57**** | 72. | 10 ± 4.16** |
| 30. | 50 ± 1.07**** | 73. | 16 ± 2.13**** |
| 31. | 49 ± 0.61**** | 74. | 10 ± 2.05* |
| 32. | 51 ± 1.07**** | 75. | 6 ± 1.23 |
| 33. | 49 ± 2.13**** | 76. | 7 ± 1.78 |
| 34. | 52 ± 0.85**** | 77. | 9 ± 1.42* |
| 35. | 52 ± 0.41**** | 78. | 9 ± 1.48* |
| 36. | 52 ± 1.60**** | 79. | 5 ± 3.64 |
| 37. | 49 ± 0.41**** | 80. | 6 ± 3.35 |
| 38. | 47 ± 2.92**** | 81. | 2 ± 2.28 |
| 39. | 49 ± 3.57**** | 82. | 11 ± 2.58* |
| 40. | 56 ± 2.761), **** | 83. | 12 ± 3.10* |
| 41. | 50 ± 0.93**** | 84. | 18 ± 1.87**** |
| 42. | 55 ± 1.201), **** | 85. | 15 ± 2.68*** |
| 86. | 18 ± 1.14**** | 130. | 3 ± 2.08 |
| 87. | 16 ± 1.55*** | 131. | 6 ± 1.91 |
| 88. | 18 ± 0.74**** | 132. | 9 ± 2.53 |
| 89. | 3 ± 3.72 | 133. | 12 ± 1.10** |
| 90. | 18 ± 2.39**** | 134. | 5 ± 2.16 |
| 91. | 12 ± 4.65** | 135. | 0 ± 2.53 |
| 92. | 18 ± 4.49**** | 136. | 0 ± 3.63 |
| 93. | 11 ± 6.36* | 137. | 5 ± 3.70 |
| 94. | 13 ± 5.21** | 138. | 0 ± 5.51 |
| 95. | 11 ± 5.28* | 139. | 0 ± 5.41 |
| 96. | 10 ± 6.70 | 140. | 2 ± 5.07 |
| 97. | 5 ± 3.72 | 141. | 0 ± 5.51 |
| 98. | 8 ± 4.23 | 142. | 1 ± 4.73 |
| 99. | 9 ± 4.23 | 143. | 7 ± 2.73 |
| 100. | 12 ± 4.49** | 144. | 5 ± 4.50 |
| 101. | 13 ± 3.36** | 145. | 19 ± 4.02**** |
| 102. | 8 ± 3.72 | 146. | 4 ± 5.12 |
| 103. | 4 ± 4.88 | 147. | 1 ± 2.20 |
| 104. | 3 ± 4.79 | 148. | 0 ± 3.70 |
| 105. | 2 ± 3.24 | 149. | 0 ± 2.91 |
| 106. | 12 ± 2.39* | 150. | 0 ± 4.41 |
| 107. | 12 ± 2.39* | 151. | 4 ± 2.51 |
| 108. | 17 ± 2.23*** | 152. | 0 ± 1.24 |
| 109. | 20 ± 1.97**** | 153. | 0 ± 0.41 |
| 110. | 21 ± 4.53**** | 154. | 0 ± 2.30 |
| 111. | 16 ± 2.23*** | 155. | 0 ± 2.89 |
| 112. | 1 ± 1.55 | 156. | 0 ± 1.09 |
| 113. | 7 ± 3.75 | 157. | 0 ± 0.71 |
| 114. | 6 ± 3.01 | 158. | 0 ± 2.30 |
| 115. | 4 ± 5.07 | 159. | 5 ± 2.30 |
| 116. | 6 ± 5.69 | 160. | 0 ± 2.58 |
| 117. | 14 ± 6.71** | 161. | 0 ± 4.59 |
| 118. | 5 ± 6.09 | 162. | 0 ± 3.11 |
| 119. | 10 ± 5.37 | 163. | 1 ± 3.27 |
| 120. | 10 ± 6.70 | 164. | 2 ± 3.30 |
| 121. | 19 ± 6.02**** | 165. | 1 ± 1.49 |
| 122. | 19 ± 4.55**** | 166. | 0 ± 5.71 |
| 123. | 12 ± 4.10* | 167. | 0 ± 4.12 |
| 124. | 13 ± 3.94* | 168. | 0 ± 3.52 |
| 125. | 6 ± 5.28 | 169. | 0 ± 2.18 |
| 126. | 6 ± 3.82 | 170. | 0 ± 4.59 |
| 127. | 5 ± 4.10 | 171. | 7 ± 9.72 |
| 128. | 0 ± 2.08 | 172. | 0 ± 0.82 |
| 129. | 5 ± 2.50 | 173. | 0 ± 3.67 |
| 174. | 5 ± 5.67 | 178. | 7 ± 3.17 |
| 175. | 7 ± 1.06 | 179. | 10 ± 2.80 |
| 176. | 12 ± 5.25* | 180. | 8 ± 4.33 |
| 177. | 12 ± 10.74* | 181. | 12 ± 3.67 |
Each extract was tested at a final concentration of 100 μg/mL, and results are presented as mean ± SD from triplicate experiments.
Differences between each extract (n = 181) and the control were assessed by one-way analysis of variance (ANOVA) followed by Dunnett’s multiple comparisons test.
Ile-Pro-Ile was used as the positive control, and the top five extracts with the highest activity.
Adjusted p-values are reported; statistical significance is denoted as
p < 0.05,
p < 0.01,
p < 0.001, and
p < 0.0001.